CBD for cancer in dogs is becoming increasingly popular. The amount of research into the effects of cannabis on cancer cells has been on the increase, and fresh data demonstrating the advantages continues to emerge. New research is only the beginning of what might be a game-changing link between cannabis and cancer therapies. There are some in particular, in fact, that relate to bladder cancer and CBD in dogs.
Bladder Cancer in Dogs
All sections of the urinary tract, including the kidneys, bladder, ureters, prostate, and urethra, can be affected by cancer. When it comes to cancer of the urinary system in dogs, however, bladder cancer is the most common diagnosis. Bladder cancer is comparatively rare relative to tumors in other regions of the body, it accounts for only 1-2 percent of all malignancies in dogs.
The most prevalent bladder cancer in dogs is invasive transitional cell carcinoma (TCC) of intermediate to high grade. TCC is a malignant tumor that spreads into the deeper layers of the bladder wall, including the bladder muscles. TCC can spread to lymph nodes and other organs in dogs.
While bladder cancer can affect any dog breed, it is more common in Scottish Terriers than in other breeds, suggesting a genetic susceptibility. It’s also more common in female dogs in their middle to senior years. Although the exact etiology of bladder cancer in dogs is unknown, a link between hereditary susceptibility and environmental variables such as pesticides and insecticides appears to exist.
Symptoms of Bladder Cancer in Dogs
Urinary straining, painful urination, increased urination and incontinence, and blood in the urine are all early indications of bladder cancer. These symptoms become more severe as the cancer advances, and if not constantly watched and treated, they can become life-threatening.
Some dogs become weak as cancer spreads to their bones or other organs in the final stages of bladder cancer. Because things like a UTI (urinary tract infection) can mimic the early signs of bladder cancer, definitive identification is critical. While UTIs are less dangerous than bladder cancer, they are still very important to manage.
Clinical signs of bladder cancer include:
- Frequent urination
- Straining while urinating
- Loss of bladder control
- Discolored urine or blood in the urine
- Urinary tract infections
Bladder cancer is notoriously difficult to detect early, and by the time symptoms appear, cancer has already progressed. It is critical to take preventive measures to prevent this malignancy or any cancer for that matter. Full-spectrum hemp extract can help support the body as a whole and defend against many inflammatory issues, including cancer, when used as part of your dog’s nutrition program, which also includes a fresh whole food diet.
CBD for Cancer
CBD’s ability to treat canine urothelial carcinoma (bladder cancer) was investigated in an encouraging study carried out in Canada.
The researchers looked at the efficacy of chemotherapy as a stand-alone treatment vs chemotherapy and CBD in combination. CBD for bladder cancer reduced cell viability and triggered cell death in canine urothelial cells on its own, but it performed even better when paired with chemotherapy, according to the study.
This research was conducted in vitro, which means it was carried out without the use of a living organism. More in vivo (within a living organism) research is needed to determine how this combination will be most successfully utilized in a therapeutic environment, as well as to be able to translate this to a human clinical setting.
Researchers are limited in their reach due to the nature of cannabis, in terms of its continuing vilification by governments domestically and globally. Research on live beings is prohibited until cannabis is rescheduled at the federal level (such as clinical trials on people).
For the time being, as much preclinical study as possible is being done in order to lay the groundwork for clinical research.
Continued Research on Bladder Cancer and CBD
The amount of research being done on the effects of cannabis on cancer cells is increasing, and fresh data demonstrating the advantages keeps coming out.
As the stigma around cannabis fades, more research is being conducted to prove that cannabis has a significant impact on cancer cells, as well as to improve existing cancer treatments.
Research is Continuing
We already know that CBD stimulates apoptosis, prevents metastasis, and has a beneficial effect when combined with chemotherapy, but additional research on specific malignancies and cannabis therapy is continually being published.
The effect of cannabidiol on canine neoplastic cell proliferation and mitogen-activated protein kinase activation during autophagy and apoptosis
How CBD oil can help dogs with cancer – All The Best Pet Care
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